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Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy
In female mammals, one of the two X chromosomes is transcriptionally silenced to equalize X-linked gene dosage relative to XY males, a process termed X chromosome inactivation. Mechanistically, this is thought to occur via directed recruitment of chromatin modifying factors by the master regulator,...
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| Hlavní autoři: | , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926064/ https://ncbi.nlm.nih.gov/pubmed/24469834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312951111 |
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