Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy

In female mammals, one of the two X chromosomes is transcriptionally silenced to equalize X-linked gene dosage relative to XY males, a process termed X chromosome inactivation. Mechanistically, this is thought to occur via directed recruitment of chromatin modifying factors by the master regulator,...

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Bibliografiske detaljer
Main Authors: Cerase, Andrea, Smeets, Daniel, Tang, Y. Amy, Gdula, Michal, Kraus, Felix, Spivakov, Mikhail, Moindrot, Benoit, Leleu, Marion, Tattermusch, Anna, Demmerle, Justin, Nesterova, Tatyana B., Green, Catherine, Otte, Arie P., Schermelleh, Lothar, Brockdorff, Neil
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926064/
https://ncbi.nlm.nih.gov/pubmed/24469834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312951111
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