A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

X-chromosome inactivation is the process that evolved in mammals to equalize levels of X-linked gene expression in XX females relative to XY males. Silencing of a single X chromosome in female cells is mediated by the non-coding RNA Xist. Although progress has been made toward identifying factors th...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Moindrot, Benoit, Cerase, Andrea, Coker, Heather, Masui, Osamu, Grijzenhout, Anne, Pintacuda, Greta, Schermelleh, Lothar, Nesterova, Tatyana B., Brockdorff, Neil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534822/
https://ncbi.nlm.nih.gov/pubmed/26190105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.053
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi