CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation

Oriented cell division is critical for cell fate specification, tissue organization, and tissue homeostasis, and relies on proper orientation of the mitotic spindle. The molecular mechanisms underlying the regulation of spindle orientation remain largely unknown. Herein, we identify a critical role...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yang, Yunfan, Liu, Min, Li, Dengwen, Ran, Jie, Gao, Jinmin, Suo, Shaojun, Sun, Shao-Cong, Zhou, Jun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926035/
https://ncbi.nlm.nih.gov/pubmed/24469800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319341111
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