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CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation

Oriented cell division is critical for cell fate specification, tissue organization, and tissue homeostasis, and relies on proper orientation of the mitotic spindle. The molecular mechanisms underlying the regulation of spindle orientation remain largely unknown. Herein, we identify a critical role...

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書誌詳細
主要な著者: Yang, Yunfan, Liu, Min, Li, Dengwen, Ran, Jie, Gao, Jinmin, Suo, Shaojun, Sun, Shao-Cong, Zhou, Jun
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926035/
https://ncbi.nlm.nih.gov/pubmed/24469800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319341111
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