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Small Molecule Inhibitors of Anthrax Lethal Factor Toxin
This manuscript describes the preparation of new small molecule inhibitors of Bacillus anthracis lethal factor. Our starting point was the symmetrical, bis-quinolinyl compound 1 (NSC 12155). Optimization of one half of this molecule led to new LF inhibitors that were desymmetrized to afford more dru...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925373/ https://ncbi.nlm.nih.gov/pubmed/24290062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.11.009 |
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