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Small Molecule Inhibitors as Countermeasures for Botulinum Neurotoxin Intoxication
Botulinum neurotoxins (BoNTs) are the most potent of known toxins and are listed as category A biothreat agents by the U.S. CDC. The BoNT-mediated proteolysis of SNARE proteins inhibits the exocytosis of acetylcholine into neuromuscular junctions, leading to life-threatening flaccid paralysis. Curre...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6259422/ https://ncbi.nlm.nih.gov/pubmed/21193845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16010202 |
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