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Inhibitors of the Metalloproteinase Anthrax Lethal Factor

Bacillus anthracis, a rod shaped, spore forming, gram positive bacteria, is the etiological agent of anthrax. B. anthracis virulence is partly attributable to two secreted bipartite protein toxins, which act inside host cells to disrupt signaling pathways important for host defense against infection...

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Bibliographic Details
Published in:Curr Top Med Chem
Main Authors: Goldberg, Allison B., Turk, Benjamin E.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5208045/
https://ncbi.nlm.nih.gov/pubmed/27072692
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