Carregando...

Identification of exosite-targeting inhibitors of anthrax lethal factor by high throughput screening

Protease inhibitor discovery has focused almost exclusively on compounds that bind to the active site. Inhibitors targeting protease exosites, regions outside of the active site that influence catalysis, offer potential advantages of increased specificity but are difficult to systematically discover...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Bannwarth, Ludovic, Goldberg, Allison B., Chen, Catherine, Turk, Benjamin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408624/
https://ncbi.nlm.nih.gov/pubmed/22840775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.05.013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!