Φορτώνει......
Identification of exosite-targeting inhibitors of anthrax lethal factor by high throughput screening
Protease inhibitor discovery has focused almost exclusively on compounds that bind to the active site. Inhibitors targeting protease exosites, regions outside of the active site that influence catalysis, offer potential advantages of increased specificity but are difficult to systematically discover...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408624/ https://ncbi.nlm.nih.gov/pubmed/22840775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.05.013 |
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