Identification of a Small-Molecule Entry Inhibitor for Filoviruses

Ebola virus (EBOV) causes severe hemorrhagic fever, for which therapeutic options are not available. Preventing the entry of EBOV into host cells is an attractive antiviral strategy, which has been validated for HIV by the FDA approval of the anti-HIV drug enfuvirtide. To identify inhibitors of EBOV...

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Detalhes bibliográficos
Main Authors: Basu, Arnab, Li, Bing, Mills, Debra M., Panchal, Rekha G., Cardinale, Steven C., Butler, Michelle M., Peet, Norton P., Majgier-Baranowska, Helena, Williams, John D., Patel, Ishan, Moir, Donald T., Bavari, Sina, Ray, Ranjit, Farzan, Michael R., Rong, Lijun, Bowlin, Terry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067866/
https://ncbi.nlm.nih.gov/pubmed/21270170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01456-10
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