The Cyp2c44 Epoxygenase Regulates Epithelial Sodium Channel Activity and the Blood Pressure Responses to Increased Dietary Salt

Hypertension is a major risk factor for cerebral, cardiovascular, and renal disease, and its prevalence and devastating consequences raises a need for new strategies for its early diagnosis and treatment. We show here that lack of a Cyp2c44 epoxygenase causes dietary salt-sensitive hypertension, a c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Capdevila, Jorge H., Pidkovka, Nataliya, Mei, Shaojun, Gong, Yan, Falck, John R., Imig, John D., Harris, Raymond C., Wang, Wenhui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Molecular Bases of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924300/
https://ncbi.nlm.nih.gov/pubmed/24368771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.508416
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