Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel

Functional and biochemical data have suggested a role for the cytochrome P450 arachidonate monooxygenases in the pathophysiology of hypertension, a leading cause of cardiovascular, cerebral, and renal morbidity and mortality. We show here that disruption of the murine cytochrome P450, family 4, subf...

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Bibliografiset tiedot
Päätekijät: Nakagawa, Kiyoshi, Holla, Vijaykumar R., Wei, Yuan, Wang, Wen-Hui, Gatica, Arnaldo, Wei, Shouzou, Mei, Shaojun, Miller, Crystal M., Cha, Dae Ryong, Price, Edward, Zent, Roy, Pozzi, Ambra, Breyer, Matthew D., Guan, Youfei, Falck, John R., Waterman, Michael R., Capdevila, Jorge H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2006
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459070/
https://ncbi.nlm.nih.gov/pubmed/16691295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27546
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