The Cyp2c44 Epoxygenase Regulates Epithelial Sodium Channel Activity and the Blood Pressure Responses to Increased Dietary Salt

Hypertension is a major risk factor for cerebral, cardiovascular, and renal disease, and its prevalence and devastating consequences raises a need for new strategies for its early diagnosis and treatment. We show here that lack of a Cyp2c44 epoxygenase causes dietary salt-sensitive hypertension, a c...

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Hlavní autoři: Capdevila, Jorge H., Pidkovka, Nataliya, Mei, Shaojun, Gong, Yan, Falck, John R., Imig, John D., Harris, Raymond C., Wang, Wenhui
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924300/
https://ncbi.nlm.nih.gov/pubmed/24368771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.508416
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