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Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver.

The products of in vivo covalent binding of activated aflatoxin B1 (AFB1) to DNA have been investigated in rats. The principal covalent product formed in liver DNA of rats treated with AFB1 has been identified as 2,3-dihydro-2-(N7-guanyl)-3-hydroxy-aflatoxin B1. This compound was isolated from the l...

詳細記述

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書誌詳細
主要な著者: Croy, R G, Essigmann, J M, Reinhold, V N, Wogan, G N
フォーマット: Artigo
言語:Inglês
出版事項: 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC392416/
https://ncbi.nlm.nih.gov/pubmed/273905
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