Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.

The covalent binding of the hepatocarcinogen aflatoxin B1 by rat liver microsomes to calf thymus DNA resulted in a binding level equal to one aflatoxin residue per 60 DNA nucleotides. An aflatoxin derivative-guanine adduct was efficiently liberated from DNA with formic acid. Analytical reversed-phas...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Essigmann, J M, Croy, R G, Nadzan, A M, Busby, W F, Reinhold, V N, Büchi, G, Wogan, G N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1977
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC431033/
https://ncbi.nlm.nih.gov/pubmed/266709
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