Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.

The covalent binding of the hepatocarcinogen aflatoxin B1 by rat liver microsomes to calf thymus DNA resulted in a binding level equal to one aflatoxin residue per 60 DNA nucleotides. An aflatoxin derivative-guanine adduct was efficiently liberated from DNA with formic acid. Analytical reversed-phas...

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出版年:	Proc Natl Acad Sci U S A
主要な著者:	Essigmann, J M, Croy, R G, Nadzan, A M, Busby, W F, Reinhold, V N, Büchi, G, Wogan, G N
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1977
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/266709/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.5.1870
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