Death by transposition – the enemy within?

Here we present and develop the hypothesis that the derepression of endogenous retrotransposable elements (RTEs) – genomic parasites – is an important and hitherto under-unexplored molecular aging process that can potentially occur in most tissues. We further envision that the activation and continu...

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Detalhes bibliográficos
Main Authors: Sedivy, John M., Kreiling, Jill A., Neretti, Nicola, De Cecco, Marco, Criscione, Steven W., Hofmann, Jeffrey W., Zhao, Xiaoai, Ito, Takahiro, Peterson, Abigail L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922893/
https://ncbi.nlm.nih.gov/pubmed/24129940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300097
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