Llwytho...

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

Replicative cellular senescence is an important tumor suppression mechanism and also contributes to aging. Progression of both cancer and aging include significant epigenetic components, but the chromatin changes that take place during cellular senescence are not known. We used formaldehyde assisted...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: De Cecco, Marco, Criscione, Steven W., Peckham, Edward J., Hillenmeyer, Sara, Hamm, Eliza A., Manivannan, Jayameenakshi, Peterson, Abigail L., Kreiling, Jill A., Neretti, Nicola, Sedivy, John M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618682/
https://ncbi.nlm.nih.gov/pubmed/23360310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12047
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