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Reorganization of chromosome architecture in replicative cellular senescence
Replicative cellular senescence is a fundamental biological process characterized by an irreversible arrest of proliferation. Senescent cells accumulate a variety of epigenetic changes, but the three-dimensional (3D) organization of their chromatin is not known. We applied a combination of whole-gen...
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Publicado no: | Sci Adv |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Association for the Advancement of Science
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788486/ https://ncbi.nlm.nih.gov/pubmed/26989773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500882 |
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