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Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues

Transposable elements (TEs) were discovered by Barbara McClintock in maize and have since been found to be ubiquitous in all living organisms. Transposition is mutagenic and organisms have evolved mechanisms to repress the activity of their endogenous TEs. Transposition in somatic cells is very low,...

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Bibliografiske detaljer
Main Authors: De Cecco, Marco, Criscione, Steven W., Peterson, Abigail L., Neretti, Nicola, Sedivy, John M., Kreiling, Jill A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883704/
https://ncbi.nlm.nih.gov/pubmed/24323947
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