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Transcriptional landscape of repetitive elements in normal and cancer human cells

BACKGROUND: Repetitive elements comprise at least 55% of the human genome with more recent estimates as high as two-thirds. Most of these elements are retrotransposons, DNA sequences that can insert copies of themselves into new genomic locations by a “copy and paste” mechanism. These mobile genetic...

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Detalhes bibliográficos
Main Authors: Criscione, Steven W, Zhang, Yue, Thompson, William, Sedivy, John M, Neretti, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122776/
https://ncbi.nlm.nih.gov/pubmed/25012247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-583
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