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Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
Replicative cellular senescence is an important tumor suppression mechanism and also contributes to aging. Progression of both cancer and aging include significant epigenetic components, but the chromatin changes that take place during cellular senescence are not known. We used formaldehyde assisted...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618682/ https://ncbi.nlm.nih.gov/pubmed/23360310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12047 |
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