Expression of FMS-like Tyrosine Kinase 3 Ligand by Oncolytic Herpes Simplex Virus Type I Prolongs Survival in Mice Bearing Established Syngeneic Intracranial Malignant Glioma

BACKGROUND: Glioblastoma is a fatal brain tumor in dire need of effective therapy. Treatments with both oncolytic viruses and immunotherapy have shown preclinical efficacy and clinical promise. We sought to exploit possible synergies between oncolytic herpes simplex virus – type I (oHSV-1) infection...

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Detaylı Bibliyografya
Asıl Yazarlar: Barnard, Zachary, Wakimoto, Hiroshi, Zaupa, Cecile, Jeyeretna, D. Sanjeeva, Patel, Anoop P., Kle, Jacqueline, Martuza, Robert L, Rabkin, Samuel D., Curry, William T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921689/
https://ncbi.nlm.nih.gov/pubmed/22653387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/NEU.0b013e318260fd73
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