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Genetic Reduction of VEGFR2 Rescues Aberrant Angiogenesis Caused by Epsin Deficiency
OBJECTIVE: We previously showed that endothelial epsin deficiency causes elevated VEGFR2 and enhanced VEGF signaling, resulting in aberrant tumor angiogenesis and tumor growth in adult mice. However, direct evidence demonstrating that endothelial epsins regulate angiogenesis specifically through VEG...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920663/ https://ncbi.nlm.nih.gov/pubmed/24311377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302586 |
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