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Epsin is required for Dishevelled stability and Wnt signaling activation in colon cancer development
Uncontrolled canonical Wnt signaling supports colon epithelial tumor expansion and malignant transformation. Understanding the regulatory mechanisms involved is crucial for elucidating the pathogenesis of and will provide new therapeutic targets for colon cancer. Epsins are ubiquitin-binding adaptor...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397653/ https://ncbi.nlm.nih.gov/pubmed/25871009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7380 |
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