Epsin is required for Dishevelled stability and Wnt signaling activation in colon cancer development

Uncontrolled canonical Wnt signaling supports colon epithelial tumor expansion and malignant transformation. Understanding the regulatory mechanisms involved is crucial for elucidating the pathogenesis of and will provide new therapeutic targets for colon cancer. Epsins are ubiquitin-binding adaptor...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Chang, Baojun, Tessneer, Kandice L., McManus, John, Liu, Xiaolei, Hahn, Scott, Pasula, Satish, Wu, Hao, Song, Hoogeun, Chen, Yiyuan, Cai, Xiaofeng, Dong, Yunzhou, Brophy, Megan L., Rahman, Ruby, Ma, Jian-Xing, Xia, Lijun, Chen, Hong
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397653/
https://ncbi.nlm.nih.gov/pubmed/25871009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7380
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki