Epsin is required for Dishevelled stability and Wnt signaling activation in colon cancer development

Uncontrolled canonical Wnt signaling supports colon epithelial tumor expansion and malignant transformation. Understanding the regulatory mechanisms involved is crucial for elucidating the pathogenesis of and will provide new therapeutic targets for colon cancer. Epsins are ubiquitin-binding adaptor...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Chang, Baojun, Tessneer, Kandice L., McManus, John, Liu, Xiaolei, Hahn, Scott, Pasula, Satish, Wu, Hao, Song, Hoogeun, Chen, Yiyuan, Cai, Xiaofeng, Dong, Yunzhou, Brophy, Megan L., Rahman, Ruby, Ma, Jian-Xing, Xia, Lijun, Chen, Hong
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397653/
https://ncbi.nlm.nih.gov/pubmed/25871009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7380
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