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Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells
Valency requirements for B cell activation upon antigen encounter are poorly understood. OB1 transnuclear B cells express an IgG1 B cell receptor (BCR) specific for ovalbumin (OVA), the epitope of which can be mimicked using short synthetic peptides to allow antigen-specific engagement of the BCR. B...
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Hauptverfasser: | , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The Rockefeller University Press
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920557/ https://ncbi.nlm.nih.gov/pubmed/24493799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131603 |
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