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Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT
Lymphocytes, such as T cells, undergo genetic V(D)J recombination, to generate a receptor with a certain specificity(1). Mice transgenic for a rearranged antigen-specific T cell receptor (TCR) have been an indispensable tool to study T cell development and function. However, such TCRs are usually is...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MyJove Corporation
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157875/ https://ncbi.nlm.nih.gov/pubmed/20972401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2168 |
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