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Transnuclear mice with pre-defined T Cell Receptor specificities against Toxoplasma gondii obtained via SCNT
Mice transgenic for rearranged antigen-specific T cell receptors (TCR) are essential tools to study T cell development and function. Such TCRs are usually isolated from the relevant T cells after long-term culture, often following repeated antigen stimulation, which unavoidably skews the T cell popu...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940321/ https://ncbi.nlm.nih.gov/pubmed/20378817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178590 |
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