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Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute‐phase Toxoplasma gondii burden

We generated a CD8 T‐cell receptor (TCR) transnuclear (TN) mouse specific to the L(d)‐restricted immunodominant epitope of GRA6 from Toxoplasma gondii as a source of cells to facilitate further investigation into the CD8 T‐cell‐mediated response against this pathogen. The TN T cells bound L(d)‐Gra6...

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Bibliografiske detaljer
Udgivet i:Immunology
Main Authors: Sanecka, Anna, Yoshida, Nagisa, Dougan, Stephanie K., Jackson, John, Shastri, Nilabh, Ploegh, Hidde, Blanchard, Nicolas, Frickel, Eva‐Maria
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046057/
https://ncbi.nlm.nih.gov/pubmed/27377596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12643
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