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Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum

The parasite Toxoplasma gondii replicates in a specialized intracellular vacuole and causes disease in many species. Protection from toxoplasmosis is mediated by CD8(+) T cells, but the T. gondii antigens and host genes required for eliciting protective immunity are poorly defined. Here we identifie...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Blanchard, Nicolas, Gonzalez, Federico, Schaeffer, Marie, Joncker, Nathalie T, Cheng, Tiffany, Shastri, Anjali J, Robey, Ellen A, Shastri, Nilabh
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976627/
https://ncbi.nlm.nih.gov/pubmed/18587399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1629
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