Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase

Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling is essential for the maintenance of normal neuronal function. Increased oxidative stress that occurs with aging was shown to impair neurovascular coupling, which likely contributes to a significa...

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Autori principali: Toth, Peter, Tarantini, Stefano, Tucsek, Zsuzsanna, Ashpole, Nicole M., Sosnowska, Danuta, Gautam, Tripti, Ballabh, Praveen, Koller, Akos, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920140/
https://ncbi.nlm.nih.gov/pubmed/24322615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00744.2013
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