Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase

Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling is essential for the maintenance of normal neuronal function. Increased oxidative stress that occurs with aging was shown to impair neurovascular coupling, which likely contributes to a significa...

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Main Authors: Toth, Peter, Tarantini, Stefano, Tucsek, Zsuzsanna, Ashpole, Nicole M., Sosnowska, Danuta, Gautam, Tripti, Ballabh, Praveen, Koller, Akos, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920140/
https://ncbi.nlm.nih.gov/pubmed/24322615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00744.2013
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