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NF-κB and STAT1 control CXCL1 and CXCL2 gene transcription

Diabetes mellitus results from immune cell invasion into pancreatic islets of Langerhans, eventually leading to selective destruction of the insulin-producing β-cells. How this process is initiated is not well understood. In this study, we investigated the regulation of the CXCL1 and CXCL2 genes, wh...

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Hlavní autoři: Burke, Susan J., Lu, Danhong, Sparer, Tim E., Masi, Thomas, Goff, Matthew R., Karlstad, Michael D., Collier, J. Jason
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920007/
https://ncbi.nlm.nih.gov/pubmed/24280128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00347.2013
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