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Strand invasion by HLTF as a mechanism for template switch in fork rescue

Stalling of replication forks at unrepaired DNA lesions can result in discontinuities opposite the damage in the newly synthesized DNA strand. Translesion synthesis or facilitating the copy from the newly synthesized strand of the sister duplex by template switching can overcome such discontinuities...

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Bibliografiske detaljer
Main Authors: Burkovics, Peter, Sebesta, Marek, Balogh, David, Haracska, Lajos, Krejci, Lumir
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919600/
https://ncbi.nlm.nih.gov/pubmed/24198246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1040
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