The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis

Successful and accurate completion of the replication of damage-containing DNA requires mainly recombination and RAD18-dependent DNA damage tolerance pathways. RAD18 governs at least two distinct mechanisms: translesion synthesis (TLS) and template switching (TS)-dependent pathways. Whereas TS is ma...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Burkovics, Peter, Dome, Lili, Juhasz, Szilvia, Altmannova, Veronika, Sebesta, Marek, Pacesa, Martin, Fugger, Kasper, Sorensen, Claus Storgaard, Lee, Marietta Y.W.T., Haracska, Lajos, Krejci, Lumir
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838361/
https://ncbi.nlm.nih.gov/pubmed/26792895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw024
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