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Strand invasion by HLTF as a mechanism for template switch in fork rescue

Stalling of replication forks at unrepaired DNA lesions can result in discontinuities opposite the damage in the newly synthesized DNA strand. Translesion synthesis or facilitating the copy from the newly synthesized strand of the sister duplex by template switching can overcome such discontinuities...

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Hlavní autoři: Burkovics, Peter, Sebesta, Marek, Balogh, David, Haracska, Lajos, Krejci, Lumir
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919600/
https://ncbi.nlm.nih.gov/pubmed/24198246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1040
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