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Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling
Defects in the ability to respond properly to an unrepaired DNA lesion blocking replication promote genomic instability and cancer. Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-bi...
שמור ב:
| הוצא לאור ב: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666394/ https://ncbi.nlm.nih.gov/pubmed/26350214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv896 |
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