HLTF’s Ancient HIRAN Domain Binds 3′-DNA Ends to Drive Replication Fork Reversal

Stalled replication forks are a critical problem for the cell because they can lead to complex genome rearrangements that underlie cell death and disease. Processes such as DNA damage tolerance and replication fork reversal protect stalled forks from these events. A central mediator of these DNA dam...

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Publicado en:Mol Cell
Main Authors: Kile, Andrew C., Chavez, Diana A., Bacal, Julien, Eldirany, Sherif, Korzhnev, Dmitry M., Bezsonova, Irina, Eichman, Brandt F., Cimprich, Karlene A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475461/
https://ncbi.nlm.nih.gov/pubmed/26051180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.05.013
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