HLTF’s Ancient HIRAN Domain Binds 3′-DNA Ends to Drive Replication Fork Reversal

Stalled replication forks are a critical problem for the cell because they can lead to complex genome rearrangements that underlie cell death and disease. Processes such as DNA damage tolerance and replication fork reversal protect stalled forks from these events. A central mediator of these DNA dam...

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Kile, Andrew C., Chavez, Diana A., Bacal, Julien, Eldirany, Sherif, Korzhnev, Dmitry M., Bezsonova, Irina, Eichman, Brandt F., Cimprich, Karlene A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475461/
https://ncbi.nlm.nih.gov/pubmed/26051180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.05.013
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