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The C-terminal Domain of Human Rev1 Contains Independent Binding Sites for DNA Polymerase η and Rev7 Subunit of Polymerase ζ
Human Rev1 is a translesion synthesis (TLS) DNA polymerase involved in bypass replication across sites of DNA damage and postreplicational gap-filling. Rev1 plays an essential structural role in TLS by providing a binding platform for other TLS polymerases that insert nucleotides across DNA lesions...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572780/ https://ncbi.nlm.nih.gov/pubmed/22828282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.07.021 |
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