Interaction between the Rev1 C-terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis

Translesion synthesis (TLS) is a mutagenic branch of cellular DNA damage tolerance that enables bypass replication over DNA lesions carried out by specialized low-fidelity DNA polymerases. The replicative bypass of most types of DNA damage is performed in a two-step process of Rev1/Polζ-dependent TL...

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Foilsithe in:Biochemistry
Main Authors: Pustovalova, Yulia, Magalhães, Mariana T. Q., D’Souza, Sanjay, Rizzo, Alessandro A., Korza, George, Walker, Graham C., Korzhnev, Dmitry M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898654/
https://ncbi.nlm.nih.gov/pubmed/26982350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01282
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