Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) ζ, and Pol κ

DNA synthesis across lesions during genomic replication requires concerted actions of specialized DNA polymerases in a potentially mutagenic process known as translesion synthesis. Current models suggest that translesion synthesis in mammalian cells is achieved in two sequential steps, with a Y-fami...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wojtaszek, Jessica, Lee, Chul-Jin, D'Souza, Sanjay, Minesinger, Brenda, Kim, Hyungjin, D'Andrea, Alan D., Walker, Graham C., Zhou, Pei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
DNA and Chromosomes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460478/
https://ncbi.nlm.nih.gov/pubmed/22859295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394841
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