Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex

The translesion synthesis (TLS) polymerases Polζ and Rev1 form a complex that enables replication of damaged DNA. The Rev7 subunit of Polζ, which is a multifaceted HORMA (Hop1, Rev7, Mad2) protein with roles in TLS, DNA repair, and cell-cycle control, facilitates assembly of this complex by binding...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rizzo, Alessandro A., Vassel, Faye-Marie, Chatterjee, Nimrat, D’Souza, Sanjay, Li, Yunfeng, Hao, Bing, Hemann, Michael T., Walker, Graham C., Korzhnev, Dmitry M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126741/
https://ncbi.nlm.nih.gov/pubmed/30111544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801149115
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