Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling

Defects in the ability to respond properly to an unrepaired DNA lesion blocking replication promote genomic instability and cancer. Human HLTF, implicated in error-free replication of damaged DNA and tumour suppression, exhibits a HIRAN domain, a RING domain, and a SWI/SNF domain facilitating DNA-bi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Achar, Yathish Jagadheesh, Balogh, David, Neculai, Dante, Juhasz, Szilvia, Morocz, Monika, Gali, Himabindu, Dhe-Paganon, Sirano, Venclovas, Česlovas, Haracska, Lajos
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666394/
https://ncbi.nlm.nih.gov/pubmed/26350214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv896
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados