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Coordinated protein and DNA remodeling by human HLTF on stalled replication fork

Human helicase-like transcription factor (HLTF) exhibits ubiquitin ligase activity for proliferating cell nuclear antigen (PCNA) polyubiquitylation as well as double-stranded DNA translocase activity for remodeling stalled replication fork by fork reversal, which can support damage bypass by templat...

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Autores principales: Achar, Yathish Jagadheesh, Balogh, David, Haracska, Lajos
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161587/
https://ncbi.nlm.nih.gov/pubmed/21795603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101951108
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