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Role of Double-Stranded DNA Translocase Activity of Human HLTF in Replication of Damaged DNA
Unrepaired DNA lesions can block the progression of the replication fork, leading to genomic instability and cancer in higher-order eukaryotes. In Saccharomyces cerevisiae, replication through DNA lesions can be mediated by translesion synthesis DNA polymerases, leading to error-free or error-prone...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812231/ https://ncbi.nlm.nih.gov/pubmed/19948885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00863-09 |
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