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Role of PCNA-dependent stimulation of 3′-phosphodiesterase and 3′–5′ exonuclease activities of human Ape2 in repair of oxidative DNA damage

Human Ape2 protein has 3′ phosphodiesterase activity for processing 3′-damaged DNA termini, 3′–5′ exonuclease activity that supports removal of mismatched nucleotides from the 3′-end of DNA, and a somewhat weak AP-endonuclease activity. However, very little is known about the role of Ape2 in DNA rep...

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Autori principali: Burkovics, Peter, Hajdú, Ildikó, Szukacsov, Valéria, Unk, Ildiko, Haracska, Lajos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715233/
https://ncbi.nlm.nih.gov/pubmed/19443450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp357
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