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Evaluating Prodrug Strategies for Esterase-Triggered Release of Alcohols
Prodrugs are effective tools in overcoming drawbacks typically associated with drug formulation and delivery. Those employing esterase-triggered functional groups are frequently utilized to mask polar carboxylic acids and phenols, increasing drug-like properties such as lipophilicity. Herein we deta...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918245/ https://ncbi.nlm.nih.gov/pubmed/23929690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300255 |
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