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Exploring Hydrogen Peroxide Responsive Thiazolidinone-Based Prodrugs
A novel approach for developing prodrugs based on masked carboxylic acids is described. Rather than using conventional esterase-based activation, thiazolidinone protecting groups have been identified that can reveal carboxylic acid groups upon activation by hydrogen peroxide. This may prove valuable...
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| Veröffentlicht in: | Chem Commun (Camb) |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4659858/ https://ncbi.nlm.nih.gov/pubmed/25811298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc09921d |
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